FRAMINGHAM, Mass.–(BUSINESS WIRE)–At WCBP 2023, SCIEX, a worldwide chief in life science analytical applied sciences, introduced the launch of the Quick Glycan Labeling and Evaluation equipment for quantitative glycan evaluation and an replace for Biologics Explorer software program to boost important protein therapeutic evaluation workflows. With these new additions, SCIEX continues to increase its skill to help the characterization of advanced and next-generation biopharmaceuticals in numerous components of the drug growth pipeline.
Biologics Explorer software program, a part of the SCIEX OS ecosystem, permits scientists to harness the complete potential of the wealthy spectrum produced from the ZenoTOF 7600 system. At this time’s launch of Biologics Explorer software program 3.0 permits streamlined middle-down protein evaluation together with single electron activated dissociation (EAD) fragmentation to yield excessive sequence protection and supply higher perception into the essential modification websites of the protein. Information are simply translated to help fast and assured choices about an important important high quality attributes for biopharmaceuticals.
As well as, the Quick Glycan Labeling and Evaluation equipment permits quick glycan heterogeneity characterization and identification whereas retaining pattern integrity and delivering constant, correct outcomes. This workflow is now suitable with the BioPhase 8800 system, which is the one multi-capillary system able to processing as much as eight samples concurrently by CE-SDS, CIEF and now glycan separation. This functionality permits a step that’s important in drug growth: monitoring adjustments in carbohydrate composition or focus that may considerably impression the general efficacy and security of a biotherapeutic.
“Each additions to our portfolio are essential options for fast and high-quality characterization of biotherapeutics,” mentioned Susan Darling, Senior Director, CE, LC, & MS Equipment, at SCIEX. “The Quick Glycan Labeling and Evaluation equipment additional accelerates already fast evaluation and identification of protein related glycans by separating by eight discrete capillaries as an alternative of just one, resulting in vital advances in total pattern throughput.”
“As well as, the growth of Biologics Explorer software program permits evaluation of subunit fragments of monoclonal antibodies on the ZenoTOF 7600 system,” mentioned Beth Hazell, Senior Director, Software program, at SCIEX. “This streamlined middle-down workflow with automated information evaluation considerably reduces effort and time on technique growth whereas offering reproducibly excessive sequence protection in a single injection.”
Additionally at WCBP, SCIEX is presenting a technical luncheon seminar on “Unifying characterization methods for novel proteins and gene remedy merchandise,” and it’s sponsoring the convention’s “Welcome reception: Dancing by the many years.”
Click on on the hyperlinks to study extra about Biologics Explorer software program and the Quick Glycan Labeling and Evaluation equipment.
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